作者： Yuanqing Cai^1,2,3;Hongxin Hu^1,2,4,3;Yang Chen^1,2,3;Jiayu Li^1,2;Chaofan Zhang^1,2;Xuhui Yuan^1,2;Wenbo Li^1,2;Changyu Huang⁵;Yiming Lin^1,2;Zeyu Zhang^1,2;Bin Yang⁶;Zida Huang^1,2CA1;Wenming Zhang^1,2CA2;Xinyu Fang^1,2CA3 （¹Department of Orthopaedic Surgery, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China;²Department of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China;³These authors contributed equally to this work.;⁴Department of Orthopaedics, Affiliated Hospital of Putian University, Putian, China;⁵Department of Orthopaedic Surgery, Quanzhou Orthopedic-traumatological Hospital, Quanzhou, China;⁶Department of Laboratory Medicine, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China）

出处： Drug Resistance Updates 2026

摘要： Aims In chronic osteomyelitis, the cortical bone serves as the primary site for long-term persistence of Staphylococcus aureus (S. aureus), the presen ...

作者： Jing Yang^1,2;Zhonghui Chen^3,2;Yue Lin¹;Cuiying Lin¹CA1;Fang Luo¹;Bin Qiu¹;Jian Wang¹;Zhenyu Lin¹CA2;Huixing Chen^4,5CA3 （¹Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fujian, Fujian 350116, PR China;²J.Y. and Z.C. contributed equally to this work. The manuscript was written through the contributions of all authors. All authors have given approval to the final version of the manuscript;³Central Laboratory, Affiliated Hospital of Putian University, Putian University, Putian, Fujian 351100, PR China;⁴Department of Hepatobiliary Surgery and Fujian Institute of Hepatobiliary Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian 350001, PR China;⁵Fujian Medical University Cancer Center, Fuzhou, Fujian 350000, PR China）

出处： Sensors and Actuators B: Chemical 2026

摘要： Elevated hyaluronidase (HAase) concentration has been found in the urine samples of the patients with bladder cancer and development of simple but sen ...

作者： Bi-Xia Huang^1,2,3;Tao Zhang^1,3;Qing-Bin Dong¹;Peng-Xing Lin²;Yi Zhou²CA1;Xin-Shuo Chen^1,2CA2 （¹Department of Neurology, The Affiliated Hospital of Putian University, Putian, China;²The School of Clinical Medicine, Fujian Medical University, China;³These authors have contributed equally to this work.）

出处： Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 2026

摘要： Iron oxide nanoparticles (IONPs) are widely applied in biomedicine and industry, yet their impact on early nervous system formation is poorly understo ...

作者： 赖越¹，林轩²，徐淼³，刘欢⁴，沈剑粦⁵，黄文华^1,6 （¹广东医科大学第一临床医学院；²莆田学院环境与生物工程学院；³福建医科大学基础医学院；⁴西南医科大学附属中医医院骨科；⁵莆田学院附属医院中心实验室；⁶南方医科大学基础医学院人体解剖学国家重点学科,广东省数字医学与生物力学重点实验室,广东省医学 3D 打印应用转化工程技术研究中心）

出处： 中国组织工程研究 2025

关键词： 骨质疏松；海洋中药；数据挖掘；网络药理学；分子对接

摘要： 背景：海洋中药为治疗骨质疏松提供了一种潜在有效且不易产生不良反应的方法。目的：应用数据挖掘和网络药理学方法分析并探讨中医临床治疗骨质疏松的用药规律及作用机制。方法：采用数据挖掘和网络药理学方法，对国家知识产权局批准的治疗骨质疏松的海洋中药专利处方进行用药模式和作用机制研究，并特别关注这些处方中的核心 ...

作者： Ying Liu^1,2;Lifang He^3,2;Meichun Huang⁴;Yuanfeng Lu¹;Huimin Xiao^1,5CA1 （¹School of Nursing, Fujian Medical University, China;²Ying Liu and LiFang He contributed equally to this study and shared the first authorship.;³School of Nursing, Putian University, China;⁴The Affiliated Hospital of Putian University, Putian City, Fujian Province, China;⁵Research Center for Nursing Humanity, Fujian Medical University, China）

出处： Nurse Education in Practice 2025

摘要： Aim To compare the effects of traditional and platform-based case-based learning (CBL) on undergraduate nursing students’ academic performance, self-e ...

作者： Xuan Lin¹;Kun Lin²;Yue Lai³;Qingping Peng⁴;Miao Xu⁵;Yiting Xu⁶;Jialin Yang⁶;Huan Liu⁷;Jianlin Shen⁸ （¹Central Laboratory, Affiliated Hospital of Putian University, Putian, Fujian Province 351100, China;Department of Environmental and Biological Engineering, Putian University, Putian, Fujian Province 351100, China;²Department of Laboratory Medicine, the Affiliated Hospital of Putian University, Putian University, Putian 351100, China;³The First Clinical Medical School, Guangdong Medical University, Zhanjiang, Guangdong Province 524002, China;⁴Collage of Integrated Traditional Chinese and Western Medicine, Southwest Medical University, Luzhou, Sichuan Province 646000, China;⁵School of Basic Medicine, Fujian Medical University, Fuzhou, Fujian Province 350100, China;⁶Department of Clinical Medicine, Putian University, Putian, Fujian Province 351100, China;⁷Department of Orthopedics, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan Province 646000, China;Corresponding author.;⁸Central Laboratory, Affiliated Hospital of Putian University, Putian, Fujian Province 351100, China;Department of Orthopedics, Affiliated Hospital of Putian University, Putian, Fujian Province 351100, China;Corresponding author at: Central Laboratory, Affiliated Hospital of Putian University, Putian, Fujian Province 351100, China.）

出处： Ecotoxicology and Environmental Safety 2025

关键词： ATBC;Network toxicology;Molecular docking;Bone metabolism

摘要： This study aims to elucidate the intricate effects of Acetyl tributyl citrate (ATBC) on bone metabolism, disentangling the underlying molecular mechan ...

作者： Xi Chen^{1 na1};Meinv Huang^{1 na1};Yi Chen¹;Haishan Xu² & …Meifang Wu¹ （¹Department of Cardiology, Affiliated Hospital of Putian University, School of Clinical Medicine, Fujian Medical University, Putian, 351100, China;²Department of Nephrology, Affiliated Hospital of Putian University, School of Clinical Medicine, Fujian Medical University, Putian, 351100, China）

出处： Heart Failure Reviews 2025

关键词： Mineralocorticoid receptor;Mineralocorticoid receptor antagonists;Heart failure with preserved ejection fraction;Phenotype;Finerenone

摘要： The mineralocorticoid receptor (MR), part of the steroid hormone receptor subfamily within nuclear hormone receptors, is found in the kidney and vario ...

作者： Jianlin Shen  ¹, Yihuang Chen  ², Yuanqun Zhang  ², Cheng Zhang  ³, Huan Liu  ⁴ （Affiliations ¹ Department of Orthopedics, Affiliated Hospital of Putian University, Putian, China; Central Laboratory, Affiliated Hospital of Putian University, China. ² Basic Medicine College, Putian University, Putian, Fujian, China. ³ Department of Trauma Center, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, China. Electronic address: zhangchengmed@163.com. ⁴ Department of Orthopedics, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan 646000, China. Electronic address: 20016040@163.com.）

出处： International journal of biological macromolecules 2025

关键词： Bone healing;IL-17;Tendon aging;Tendon ossification.

摘要： The interleukin-17 (IL-17) family, encompassing IL-17A to IL-17F, plays pivotal roles across various biomedical fields. IL-17A, a prominent cytokine, ...

作者： Lan-Ting Huang  ¹, Xiao-Yan Zheng  ², Zhi-Hong Zhang  ², Hong-Yan Zheng  ³, Xin Wei  ⁴, Ji-Yan Yang  ⁵, Li-Hua Zhang  ⁶, Xiu-Qin Lu  ⁷, Ying-Qing Yang  ⁸, Jin-Xia Lin  ⁹, Chun-Mei Zhang  ¹⁰, Li-Ping Luo  ¹¹, Dong-Hua Jiang  ¹², Shao-Hua Huang  ¹³, Xiu-Bi Huang  ¹⁴, Yue-Mei Zhan  ¹⁵, Wen-Zhu Xu  ¹⁶, Wei Han  ^{17   18}, Fu-Yuan Hong  ¹⁹ （Affiliations ¹ Department of Nephrology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, Fujian, China. lanne_huang@foxmail.com. ² Department of Blood Purification, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, Fujian, China. ³ Department of Blood Purification, Renhe Hospital of Hubei Three Gorges University, Yichang, Hubei, China. ⁴ Department of Blood Purification, Xinjiang Changji Hui Autonomous Prefecture Hospital of Traditional Chinese Medicine, Changji, Xinjiang, China. ⁵ Department of Blood Purification, Pengyang People's Hospital of Ningxia Hui Autonomous Region, Pengyang, Ningxia, China. ⁶ Department of Blood Purification, Fuzhou First Hospital, Fuzhou, Fujian, China. ⁷ Department of Blood Purification, Fuzhou General Hospital, Fuzhou, Fujian, China. ⁸ Department of Blood Purification, Affiliated Hospital of Putian University, Putian, Fujian, China. ⁹ Department of Blood Purification, Quanzhou First Hospital, Quanzhou, Fujian, China. ¹⁰ Department of Blood Purification, Wuyishan Municipal Hospital, Wuyishan, Fujian, China. ¹¹ Department of Blood Purification, Nanping People's Hospital, Nanping, Fujian, China. ¹² Department of Blood Purification, Sanming Second Hospital, Sanming, Fujian, China. ¹³ Department of Blood Purification, Sanming First Hospital, Sanming, Fujian, China. ¹⁴ Department of Blood Purification, Zhangzhou Hospital, Zhangzhou, Fujian, China. ¹⁵ Department of Blood Purification, Longyan First Hospital, Longyan, Fujian, China. ¹⁶ Department of Blood Purification, Ningde Mindong Hospital, Mindong, Fujian, China. ¹⁷ Department of Nephrology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, Fujian, China. ¹⁸ Department of Blood Purification, Xiamen Zhongshan Hospital, Xiameng, Fujian, China. ¹⁹ Department of Nephrology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, Fujian, China. hongdoc@163.com.）

出处： Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2025

作者： Junting Weng ^{#  1   2}, Shuoyun Weng ^{#  3}, Jitao Xu ^{#  1   2}, Danjuan Liu  ^{1   2}, Rongjie Guo  ^{1   2}, Bingbing Shi  ^{1   2}, Min Chen  ^{4   5} （Affiliations ¹ Department of Clinical Medicine, Fujian Medical University, Fuzhou, 350000, China. ² Department of Critical Care Medicine, the Affiliated Hospital of Putian University, No. 999 Dongzhen East Road, Licheng District, Putian, 351100, China. ³ Wenzhou Medical University School of Optometry and Ophthalmology, Wenzhou, 325035, China. ⁴ Department of Clinical Medicine, Fujian Medical University, Fuzhou, 350000, China. ptfsyy65581@163.com. ⁵ Department of Critical Care Medicine, the Affiliated Hospital of Putian University, No. 999 Dongzhen East Road, Licheng District, Putian, 351100, China. ptfsyy65581@163.com.）

出处： Naunyn-Schmiedeberg's archives of pharmacology 2025

关键词： Acute lung injury;Apoptosis;Inflammation;Oxidative stress;PI3K/AKT;Respiratory function;Tocilizumab.

摘要： Acute lung injury (ALI) is a severe inflammatory condition of the respiratory system, associated with high morbidity and mortality. This study investi ...