作者： Shaorui Zheng  ¹, Shuwen Mu  ², Jun Li  ³, Shangming Zhang  ³, Liangfeng Wei  ³, Mingyue Wang  ⁴, Yongjun Xu  ⁵, Shousen Wang  ⁶ （Affiliations ¹ Fuzong Clinical Medical College of Fujian Medical University, Fuzhou 350025, China; Department of Neurosurgery, Affiliated Hospital of Putian University, Putian 351100, China. ² Fuzong Clinical Medical College of Fujian Medical University, Fuzhou 350025, China. ³ Department of Neurosurgery, The 900th Hospital of Joint Logistic Support Force, Fujian Medical University Fuzong Clinical College, Fuzhou 350025, China. ⁴ Department of Pathology, The 900th Hospital of Joint Logistic Support Force, Fujian Medical University Fuzong Clinical College, Fuzhou 350025, China. ⁵ Laboratory of Basic Medicine, The 900th Hospital of Joint Logistic Support Force, Fujian Medical University Fuzong Clinical College, Fuzhou 350025, China. Electronic address: xuyongjun221123@126.com. ⁶ Fuzong Clinical Medical College of Fujian Medical University, Fuzhou 350025, China; Department of Neurosurgery, The 900th Hospital of Joint Logistic Support Force, Fujian Medical University Fuzong Clinical College, Fuzhou 350025, China. Electronic address: wshsen@126.com.）

出处： Brain research 2022

关键词： Cerebral blood flow;Intracranial pressure;Traumatic brain injury.

摘要： Traumatic brain injury (TBI) is a serious public health problem that endangers human health and is divided into primary and secondary injuries. Previo ...

作者： Ling-Feng Zhang  ¹, Yi-Pan Zhang  ¹, Peng-Xing Lin  ¹, Li-Hong Xue  ¹ （Affiliation ¹ Neurology department, The Affiliated Hospital of Putian University, Putian, Fujian, China.）

出处： Pakistan journal of pharmaceutical sciences 2022

摘要： To evaluate the efficacy and safety of sodium oligomannate in the treatment of Alzheimer's disease. Patients with mild-to-moderate AD were randomly di ...

作者： Tian-jiao Song¹;Xiao-hong Lin²;Ping-ting Huang³;Yu-qing Chen³;Li-min Chen³ （¹Department of Emergency, Fujian Provincial Hospital;²Department of Respiratory Medicine, The Affiliated Hospital of Putian University;³Department of Respiratory Medicine, Affiliated Union Hospital of Fujian Medical University）

出处： Scientific Reports 2022

摘要： Lung cancer is the most malignant form of cancer and has the highest morbidity and mortality worldwide. Due to drug resistance, the current chemothera ...

作者： Peng Zhou  ¹, Heng Meng  ², Xiaoyu Liang  ¹, Xiaoyun Lei  ², Jingwen Zhang  ³, Wenjun Bian  ¹, Na He  ¹, Zhijian Lin  ⁴, Xingwang Song  ¹, Weiwen Zhu  ¹, Bin Hu  ¹, Bingmei Li  ¹, Limin Yan  ⁵, Bin Tang  ¹, Tao Su  ¹, Hankui Liu  ⁶, Yong Mao  ⁶, Qiongxiang Zhai  ³, Yonghong Yi  ¹ （Affiliations ¹ Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Department of Neurology, Institute of Neuroscience, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China. ² Department of Neurology, The First Affiliated Hospital of Jinan University, Clinical Neuroscience Institute of Jinan University, Guangzhou, China. ³ Department of Pediatrics, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China. ⁴ Department of Neurology, Affiliated Hospital of Putian University, Putian, China. ⁵ Department of Neurology, The Second Affiliated Hospital of Hainan Medical University, Haikou, China. ⁶ BGI-Shenzhen, Shenzhen, China.）

出处： Frontiers in molecular neuroscience 2022

关键词： ADGRV1;audio-visual disorders;febrile seizures;genotype-phenotype correlation;submolecular effect.

摘要： Objective: ADGRV1 gene encodes adhesion G protein-coupled receptor-V1 that is involved in synaptic function. ADGRV1 mutations are associated with audi ...

作者： Yanfang Li¹;Zhiqing Wu¹;Jianlin Shen² （¹Department of Pediatric Surgery, Affiliated Hospital of Putian University, #181 Meiyuan East Road, Putian, 351100, Fujian, China;²Department of Orthopedics, Affiliated Hospital of Putian University, #999 Dongzhen East Road, Putian, 351100, Fujian, China;Corresponding author.）

出处： Regenerative Therapy 2022

关键词： Osteosarcoma;hsa_circ_0000885;miR-16-5p;E2F3;Cancer stem cell

摘要： Introduction: Accumulating evidence has shown that circular RNAs (circRNAs) have indispensable functions during tumor progression by regulating gene e ...

作者： 庄耀宁，陈一媛，林敏，黄美春，林群英 （莆田学院附属医院呼吸与危重症医学科监护室；莆田学院附属医院护理部）

出处： 中华护理杂志 2022

关键词： 多发性内分泌瘤病；儿茶酚胺心肌病；嗜铬细胞瘤；心脏停搏；护理

摘要： 总结1例多发性内分泌瘤病2A型并发儿茶酚胺心肌病患者突发心搏骤停的护理经验。护理主要内容如下:组建多学科团队,制订诊疗方案;减少刺激,避免诱发高血压危象;儿茶酚胺心肌病危象的识别与急救护理;体外膜肺氧合与血液净化生命支持的护理;目标体温管理。患者入院第15天病情稳定,顺利转科继续治疗。

作者： 胡伟群，陈秀芬，黄金樵，茅林蔚，潘志勇，蒋远伟 （莆田学院附属医院；福建医科大学）

出处： 中国病原生物学杂志 2022

关键词： 鼻咽癌；菌群分布；耐药性；gyrA基因

摘要： 目的 探究鼻咽癌患者鼻咽部菌群分布，对于鼻咽癌患者临床治疗进程具有积极推进作用。方法 收集鼻咽部分泌物样本，采用全自动微生物鉴定仪鉴定菌株，采用琼脂稀释法分析表皮葡萄球菌和草绿色链球菌的耐药期刊。PCR扩增、基因测序分析耐药基因变异情况。结果 2014-2019年鼻咽癌患者鼻咽部分离菌株112株，各 ...

作者： 陈一媛，林敏，黄美春，张奕馨，许晓宇，林丹丹，庄耀宁 （莆田学院附属医院呼吸与危重症医学科监护室；莆田学院附属医院护理部）

出处： 中华护理杂志 2022

关键词： 重症监护病房；膈；机械通气；知识；态度；行为；调查问卷；护理管理研究

摘要： 目的 了解福建省ICU护士对呼吸机相关性膈肌功能障碍(ventilator-induced diaphragm dysfunction,VIDD护理知信行的现状，分析其影响因素。方法 采用便利抽样法，于2021年4月采用自行编制的VIDD护理知信行问卷对福建省11所三级医院的ICU护士进行问卷调查。 ...

作者： 林国钦¹；林俊敏¹；翁志成²；林丽明¹；许开祖¹；陈晓敏¹；翁育娟³；卓建伟¹；吴梅芳¹ （¹福建省莆田学院附属医院心血管内科；²福建省莆田学院介入科；³福建省莆田学院超声科）

出处： 中国循环杂志 2022

关键词： 微球室间隔消融术；肥厚型心肌病；安全性；有效性

摘要： 目的：评价微球室间隔心肌消融术（MSA）治疗肥厚型梗阻性心肌病（HOCM）的安全性和有效性。方法：回顾性纳入2019 年6 月至2021 年2 月在莆田学院附属医院心血管内科接受MSA（应用微粒球替代无水酒精行室间隔心肌消融术）治疗的HOCM 患者10 例。分析MSA 术前、术后1 周、1 个月、3 ...

作者： 林敏^1,2；王阳阳^1,3；谷嘉宁^1,4；陈湘^1,5；张京煜¹ （¹北京协和医学院护理学院；²莆田学院附属医院；³北京协和医院；⁴北京回龙观医院；⁵北京大学第一医院）

出处： 护理学杂志 2022

关键词： 护理；学生；志愿服务；参与率；服务形式；服务内容；障碍因素

摘要： 目的 了解北京市高等医学院校护理专业学生志愿服务现状，为构建更完善的护理专业学生志愿服务体系提供依据。方法 采用便利抽样法，以网络问卷调查的形式对北京市4所高等医学院院校护理学院的1 077名学生开展调查。结果 护理专业学生志愿服务活动参与者1 059人(98.33%)，比较和非常赞同志愿活动能丰富 ...