作者: 何俊伟,薛丽虹,张一攀 (莆田学院附属医院神经内科)
出处: 中华航海医学与高气压医学杂志 2021
关键词: 缺血性脑卒中;阿替普酶;动脉溶栓;高压氧;可溶性细胞间黏附分子-1;碱性成纤维细胞生长因子
摘要: 目的探讨高压氧联合阿替普酶动脉溶栓治疗缺血性脑卒中的效果及其对血清可溶性细胞间黏附分子-1(soluble intercellular adhesion molecule-1, sICAM-1)、碱性成纤维细胞生长因子(basic fibroblast growth factor, bFGF)水平的 ...
作者: Zhu Shuang,Yang Bingsheng,Li Sijing,Tong Ge,Tan Jianye,Wu Guofeng,Li Lin,Chen Guoli,Chen Qian,Lin Lijun (Department of Joint and Orthopedics, Zhujiang Hospital, Southern Medical University, Guangdong, Guangzhou;Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangdong, Guangzhou;Department of Orthopedics, Affiliated Hospital of Putian University, Fujian, Putian;Cell and Molecular Biology Laboratory, Department of Orthopaedics, Alpert Medical School of Brown University/Rhode Island Hospital, USA, Providence)
出处: Neural Regeneration Research 2021
关键词: extracellular;matrix;function;impairment;glial;scar;nerve;regeneration;neuropathic;pain;post-translational;modification;spinal;cord;injury;therapeutic;target
摘要: Deficits in intrinsic neuronal capacities in the spinal cord, a lack of growth support, and suppression of axonal outgrowth by inhibitory molecules me ...
作者: 张艳,曾丽娜,林荔 (莆田学院附属医院产前诊断中心)
出处: 中华医学遗传学杂志 2021
摘要: 孕妇40岁,G_(1)P_(1),首次妊娠为空孕囊,第2次为宫外孕。第3次妊娠孕23周超声提示胎儿为草莓头、小脑蚓部及鼻骨缺失,小下颌、永存左上腔静脉;羊水检查发现21三体,选择引产。孕妇表型、智力均正常,外周血染色体核型为46,XX,t(9;11)(q22;q23)(图1)。[第一段]
作者: 方雪婷,陈智伟,蔡素琴,吴春林,曾冬钰,宋伟伟 (福建医科大学附属第二医院病理科;莆田学院附属医院病理科)
出处: 临床与实验病理学杂志 2021
关键词: 子宫肿瘤;类似卵巢性索肿瘤的子宫肿瘤;免疫组织化学;荧光原位杂交
摘要: 目的探讨类似卵巢性索肿瘤的子宫肿瘤(uterine tumor resembling ovarian sex cord tumor, UTROSCT)的临床病理学特征、分子遗传学改变及其鉴别诊断。方法回顾性分析6例UTROSCT的临床病理学特征、免疫表型等。采用FISH检测JAZF1基因及NCOA2 ...
作者: Qiyue Chen,Zhongliang Ning,Zhiyu Liu,Yanbing Zhou,Qingliang He,Yantao Tian,Hankun Hao,Wei Lin,Lixin Jiang,Gang Zhao,Ping Li,Chaohui Zheng,Changming Huang (Department of Gastric SurgeryFujian Medical University Union Hospital;Department of General SurgeryFujian Medical University Union Hospital;Key Laboratory of Ministry of Education of Gastrointestinal CancerFujian Medical University;Fujian Key Laboratory of Tumor MicrobiologyFujian Medical University;Department of Gastrointestinal SurgeryWest District of the First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of China;Department of Gastrointestinal SurgeryAffiliated Hospital of Qingdao University;Department of Gastrointestinal Surgerythe First Affiliated Hospital of Fujian Medical University;Department of Pancreatic and Gastric SurgeryNational Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical College;Department of General SurgeryHuashan HospitalFudan University;Department of Gastrointestinal Surgery and Gastrointestinal Surgery Research Institutethe Affiliated Hospital of Putian University;Department of Gastrointestinal SurgeryYantai Yuhuangding Hospital;Department of Gastrointestinal SurgeryRenji HospitalShanghai Jiaotong University)
出处: Chinese Journal of Cancer Research 2021
作者: 张超凤,刘晓莉,李雪娟,林琦,林海滨 (莆田学院附属医院血液风湿科;莆田学院药学与医学技术学院;莆田学院附属医院药学部;莆田学院附属医院骨科)
出处: 中国新药杂志 2021
关键词: 痛风急性发作期;非甾体抗炎药;选择性COX-2受体抑制剂;糖皮质激素;秋水仙碱;药物经济学
摘要: 系统评价非甾体抗炎药(NSAIDs)、选择性COX-2受体抑制剂(COXIBs)、糖皮质激素(GC)及秋水仙碱(COLC)治疗痛风急性发作的有效性、安全性与经济性。方法:检索Medline, Embase, CENTRAL,CBM,CNKI等文献数据库,检索NSAIDs, COXIBs, GC及CO ...
作者: 陈仲辉,李金秋,林伟,俞柳敏,涂海健,陈宇,蔡宗苇,林振宇 (莆田学院附属医院;食品安全与生物分析教育部重点实验室福州大学化学学院;香港浸会大学环境与生物分析国家重点实验室)
出处: 高等学校化学学报 2021
作者: 何俊伟,薛丽虹,张一攀 (莆田学院附属医院神经内科)
出处: 免疫学杂志 2021
关键词: 缺血性脑梗死;骨髓间充质干细胞;T辅助细胞17;调节性T细胞;JAK/STAT
摘要: 目的探究骨髓间充质干细胞(bone marrow mesenchymal stem cells,BMSCs)移植通过JAK/STAT通路对缺血性脑梗死大鼠T辅助细胞17(T help 17cells,Th17)/调节性T细胞(regulatory T cells,Treg)平衡以及神经元炎性和凋亡的 ...
作者: 林琦,李紫如,郭锦玲,严晓萍,郑伟男,林群英 (莆田学院附属医院药学部;莆田学院药学与医学技术学院;肿瘤转化医学福建省高校重点实验室;莆田学院附属医院呼吸与危重症医学科)
出处: 中国新药杂志 2021
关键词: 慢性阻塞性肺疾病;标准桃金娘油;核因子E2相关因子2;血红素加氧酶1;氧化应激
摘要: 目的:观察标准桃金娘油(myrtol standardized, MS)对慢性阻塞性肺疾病(COPD)大鼠核因子E2相关因子2(Nrf2)/血红素加氧酶1(HO-1)通路的影响,探讨标准桃金娘油治疗COPD可能的作用机制。方法:将Wistar大鼠随机分为4组,1组为空白对照组(CON),另外3组首先 ...
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