"神经外科是我院较早独立建科的科室，经过近几十年的建设和发展，现已成为我市神经外科临床、教学、科研和人才培训中心。 一、学科队伍：科室现有医生12人，其中主任医师3人、副主任医师4人、主治医师2人、具有硕士学位5人，在读博士1人。学科带头人方志敏教授系福建省神经外科学会常务委员，是我市本学... [详细]
作者： Yuanbao Kang 1, Quanming Zhou 2 （Affiliations 1 Department of Neurosurgery, Affiliated Hospital of Putian University, 351100 Putian, Fujian, China; Department of Clinical Medicine, Fujian Medical University, 350122 Fuzhou, Fujian, China. 2 Department of Neurosurgery, Affiliated Hospital of Putian University, 351100 Putian, Fujian, China.）
出处： Annali italiani di chirurgia 2025
摘要： Aim: This study aims to investigate the impact of neuroendoscopic surgery on cerebral hemodynamics and functional recovery in patients with different ...
作者： 周权明，吴设娟，张建鹤，黄建煌，陈耀，黄迢华 （莆田学院附属医院神经外科）
出处： 中国临床药理学杂志 2024
关键词： 甘草酸；水通道蛋白4；创伤性脑损伤；细胞活性；神经元
摘要： 目的 探究甘草酸对创伤性脑损伤（TBI）大鼠神经元损伤的作用，以及其可能机制。方法 将大鼠随机分为假手术组、模型组、对照组和低、中、高剂量实验组，每组20只。假手术组仅进行颅脑开孔处理；其余5组大鼠用体外冲击法建立TBI模型。于建模后的0、24、48 h,低、中、高剂量实验组分别腹腔注射10、50、 ...
作者： Yao Chen # 1, Jian-Huang Huang # 2, Yuan-Bao Kang 1, Zheng-Jian Yao 1, Jian-Hua Song 1 （Affiliations 1 Department of Neurosurgery, Affiliated Hospital of Putian University, Putian, Fujian Province, China. 2 Department of Neurosurgery, Affiliated Hospital of Putian University, Putian, Fujian Province, China. teamhuang@sina.com.）
出处： BMC medical genomics 2024
关键词： Bioinformatics analysis;Crosstalk genes;Immune infiltration;Intracranial aneurysms;Periodontitis.
摘要： Objectives: The risk of intracranial aneurysms (IAs) development and rupture is significantly higher in patients with periodontitis (PD), suggesting a ...
作者： Jian-Huang Huang # 1, Yao Chen # 2, Yuan-Bao Kang 2, Zheng-Jian Yao 2, Jian-Hua Song 2 （Affiliations 1 Department of Neurosurgery, Affiliated Hospital of Putian University, Putian, Fujian, China. teamhuang@ptu.edu.cn. 2 Department of Neurosurgery, Affiliated Hospital of Putian University, Putian, Fujian, China.）
出处： Scientific reports 2024
关键词： Bioinformatics analysis;Crosstalk genes;Glioblastoma;Immune infiltration;Periodontitis.
摘要： Despite clinical and epidemiological evidence suggestive of a link between glioblastoma (GBM) and periodontitis (PD), the shared mechanisms of gene re ...
作者： Jianhuang Huang 1, Guiting You 2, Quan Chen 2, Yunpeng Lin 3, Yijing Lin 3, Yu Liang 3, Caihou Lin 2, Jianwu Chen 4 5 6 （Affiliations 1 Department of Neurosurgery, Affiliated Hospital of Putian University, Putian 351100, China. 2 Department of Neurosurgery, Fujian Medical University Union Hospital, Fuzhou 350001, China. 3 School of Basic Medical Sciences, Fujian Medical University, Fuzhou 350122, China. 4 Department of Radiation Oncology, Fujian Medical University Union Hospital, Fuzhou, Fujian province, China. 5 Fujian Key Laboratory of Intelligent Imaging and Precision Radiotherapy for Tumors (Fujian Medical University), Fuzhou, Fujian province, China. 6 Clinical Research Center for Radiology and Radiotherapy of Fujian Province (Digestive, Hematological and Breast Malignancies), Fuzhou, Fujian province, China.）
出处： Current medicinal chemistry 2024
关键词： CD8A;ICAM1;IL7R;bioinformatics analysis;diffuse midline glioma (DMG);immunosuppression;single-cell analysis.
摘要： Background: Diffuse midline gliomas (DMG) pose a grave threat as a malignant tumor primarily affecting children in the pons region. These tumors exhib ...
作者： Nan Lin 1, Rudy Paul 2, Santiago Guerra 2, Yan Liu 1 3, James Doulgeris 4, Min Shi 5 6, Maohua Lin 4, Erik D Engeberg 2 4 7, Javad Hashemi 4, Frank D Vrionis 3 （Affiliations 1 Department of Gastroenterology, The Affiliated Hospital of Putian University, Putian 351100, China. 2 Department of Ocean & Mechanical Engineering, Florida Atlantic University, Boca Raton, FL 33431, USA. 3 Department of Neurosurgery, Marcus Neuroscience Institute, Boca Raton Regional Hospital, Boca Raton, FL 33486, USA. 4 Department of Biomedical Engineering, Florida Atlantic University, Boca Raton, FL 33431, USA. 5 Harvard Ophthalmology AI Lab, Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02115, USA. 6 School of Computing and Informatics, University of Louisiana, Lafayette, LA 70504, USA. 7 Center for Complex Systems and Brain Science, Florida Atlantic University, Boca Raton, FL 33431, USA.）
出处： Healthcare (Basel, Switzerland) 2024
关键词： Artificial Intelligence (AI);healthcare;medical imaging;smart healthcare systems;surgery.
摘要： Artificial Intelligence (AI) is poised to revolutionize numerous aspects of human life, with healthcare among the most critical fields set to benefit ...
作者： Guiting You;Zhenyu Zheng;Yulong Huang;Guifen Liu;Wei Luo;Jianhuang Huang;Longjin Zhuo;Binghua Tang;Shunyi Liu;Caihou Lin （Affiliations 1 Department of Neurosurgery, Fujian Medical University Union Hospital, Fuzhou, China. 2 Fujian Medical University, Fuzhou, China. 3 Department of Gynaecology, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China. 4 Department of Neurosurgery, Affiliated Hospital of Putian University, Putian, China. 5 Pingtan Comprehensive Experimental Area Hospital, Fuzhou, China.）
出处： CNS neuroscience & therapeutics 2023
关键词： immune microenvironment;intercellular interaction;recurrent malignant glioma;single-cell RNA sequencing;tumor-associated macrophages.
摘要： Aims: Tumor-associated macrophages (TAMs) in the immune microenvironment play an important role in the increased drug resistance and recurrence of mal ...
作者：
Yangping Zhuang1,2,6;Shaohuai Xia3;Junwei Chen4;Jun Ke1,6;Shirong Lin1,6;Qingming Lin1,6;Xiahong Tang1,6;Hanlin Huang1,6;Nan Zheng1,6;Yi Wang5;Feng Chen1,6
出处： European Journal of Medical Research 2023
关键词： Acute upper gastrointestinal bleeding;Rebleeding;AIMS65 score;Nomogram;Predictive model
摘要： Background The incidence of rebleeding in patients with upper gastrointestinal bleeding (UGIB) remains despite advances in intervention approaches. T ...
作者： Long Lin # 1, Shaorui Zheng # 2, Jinqing Lai 3, Dan Ye 4, Qiaomei Huang 5, Zhe Wu 3, Xiangrong Chen 6, Shousen Wang 7 （Affiliations 1 Department of Neurosurgery, Fuzong Clinical Medical College, Fujian Medical University, Fuzhou, 350025, Fujian Province, China. 2 Department of Neurosurgery, Affiliated Hospital of Putian University, Putian, 351100, Fujian Province, China. 3 Department of Neurosurgery, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, 362000, Fujian Province, China. 4 Fujian University of Traditional Chinese Medicine, Fuzhou, 350025, Fujian Province, China. 5 Department of Anaesthesiology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, 362000, Fujian, China. 6 Department of Neurosurgery, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, 362000, Fujian Province, China. xiangrong_chen281@126.com. 7 Department of Neurosurgery, 900th Hospital, Fuzhou, 350025, Fujian Province, China. wshsen1965@126.com.）
出处： Molecular neurobiology 2023
关键词： ADAM17;Exosome;Microglia;Nerve growth factor;Omega-3 polyunsaturated fatty acid;TNF-α/NF-κB pathway;Traumatic brain injury.
摘要： The transformation of microglia to a pro-inflammatory phenotype at the site of traumatic brain injury (TBI) drives the progression of secondary neurod ...
作者： 王磊，黄建煌，黄迢华，林金加，陈建宁，宋建华，姚正健 （莆田学院附属医院神经外科；莆田学院附属医院介入导管室）
出处： 中华神经医学杂志 2022
关键词： 颅内动脉瘤；椎动脉夹层动脉瘤；双支架后释放技术；血管内治疗
摘要： 目的:评估双支架后释放技术辅助弹簧圈栓塞治疗颅内破裂椎动脉夹层动脉瘤(VADAs)的疗效和安全性。方法:选择莆田学院附属医院神经外科自2015年9月至2020年3月采用双支架后释放技术辅助弹簧圈栓塞治疗的17例颅内破裂VADAs患者(17个动脉瘤)，术后即刻行DSA检查评估VADAs的栓塞程度，随访 ...
