作者： Yuanqing Cai^1,2,3;Hongxin Hu^1,2,4,3;Yang Chen^1,2,3;Jiayu Li^1,2;Chaofan Zhang^1,2;Xuhui Yuan^1,2;Wenbo Li^1,2;Changyu Huang⁵;Yiming Lin^1,2;Zeyu Zhang^1,2;Bin Yang⁶;Zida Huang^1,2CA1;Wenming Zhang^1,2CA2;Xinyu Fang^1,2CA3 （¹Department of Orthopaedic Surgery, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China;²Department of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China;³These authors contributed equally to this work.;⁴Department of Orthopaedics, Affiliated Hospital of Putian University, Putian, China;⁵Department of Orthopaedic Surgery, Quanzhou Orthopedic-traumatological Hospital, Quanzhou, China;⁶Department of Laboratory Medicine, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China）

出处： Drug Resistance Updates 2026

摘要： Aims In chronic osteomyelitis, the cortical bone serves as the primary site for long-term persistence of Staphylococcus aureus (S. aureus), the presen ...

作者： Jing Yang^1,2;Zhonghui Chen^3,2;Yue Lin¹;Cuiying Lin¹CA1;Fang Luo¹;Bin Qiu¹;Jian Wang¹;Zhenyu Lin¹CA2;Huixing Chen^4,5CA3 （¹Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fujian, Fujian 350116, PR China;²J.Y. and Z.C. contributed equally to this work. The manuscript was written through the contributions of all authors. All authors have given approval to the final version of the manuscript;³Central Laboratory, Affiliated Hospital of Putian University, Putian University, Putian, Fujian 351100, PR China;⁴Department of Hepatobiliary Surgery and Fujian Institute of Hepatobiliary Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian 350001, PR China;⁵Fujian Medical University Cancer Center, Fuzhou, Fujian 350000, PR China）

出处： Sensors and Actuators B: Chemical 2026

摘要： Elevated hyaluronidase (HAase) concentration has been found in the urine samples of the patients with bladder cancer and development of simple but sen ...

作者： Bi-Xia Huang^1,2,3;Tao Zhang^1,3;Qing-Bin Dong¹;Peng-Xing Lin²;Yi Zhou²CA1;Xin-Shuo Chen^1,2CA2 （¹Department of Neurology, The Affiliated Hospital of Putian University, Putian, China;²The School of Clinical Medicine, Fujian Medical University, China;³These authors have contributed equally to this work.）

出处： Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 2026

摘要： Iron oxide nanoparticles (IONPs) are widely applied in biomedicine and industry, yet their impact on early nervous system formation is poorly understo ...

作者： Ruina Luan¹, Hanbin Lin², Xin Zhao^{1 3}, Jianpeng Li⁴, Maohe Chen², Shiping Luo⁵, Xinjian Lin^{2 6} （Affiliations ¹ School of Basic Medical Sciences, Key Laboratory of Translational Tumor Medicine in Fujian Province, Putian University, Putian, Fujian, China. ² Central Laboratory, Affiliated Hospital of Putian University, Putian, Fujian, China. ³ Department of Pediatric Orthopaedics, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China. ⁴ Department of Breast Surgery, Affiliated Hospital of Putian University, Putian, Fujian, China. ⁵ Department of Breast Surgical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian, China. ⁶ Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, Fujian, China.）

出处： Clinical and translational medicine 2026

关键词： DCAF7;Wnt signalling;hepatocellular carcinoma;immune infiltration;pan‐cancer.

摘要： Background: DDB1 and CUL4-associated factor 7 (DCAF7) is a WD-repeat adaptor that recruits substrates to the CUL4DDB1 ubiquitinligase complex, but its ...

作者： Nan Jin^{1 2}, Yaling Chen¹, Huangyu Luo¹, Yanhong Su¹, Yumin Weng¹, Xin Lin¹, Tingting Zheng¹, Bingbing Li^{3 4}, Tianhui Liu^{1 2}, Jianmin Chen^{1 2} （Affiliations ¹ College of Pharmacy and Medical Technology, Putian University, Putian, Fujian, China. ² Key Laboratory of Pharmaceutical Analysis and Laboratory Medicine (Putian University), Putian, Fujian, China. ³ Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Putian University, Putian, Fujian, China. ⁴ Department of Respiratory and Critical Care Medicine, Putian Pulmonary Hospital, Putian, Fujian, China.）

出处： Drug delivery 2026

关键词： Psoriasis recurrence;blue light;microbiome;nitric oxide;splenomegaly.

摘要： The recurrence following the discontinuation of medication is a formidable challenge in managing psoriasis. Changes in the microbiome accompany the on ...

作者： Lei Gu ^#1, Jing Lin ^#2, Anmao Li ^#3, Jian Yue ^#4, Wen Wen ^#5, Wei Liu ^#5, Qunying Lin⁶, Xiangqi Chen⁷, Xiaohong Chen⁸, Jun Wu⁹, Zeyi Liu¹⁰, Baosong Xie¹¹, Guoxiang Lai¹², Jian-An Huang¹³ （Affiliations ¹ Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China. ² Department of Infectious Diseases, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China. ³ Department of Rheumatology and Immunology, Affliated Hospital of Zunyi Medical University, Zunyi, 563000, China. ⁴ The People's Hospital of Gaozhou, Gaozhou, 525200, China. ⁵ Department of Pulmonary and Critical Care Medicine, Fuzong Clinical Medical College of Fujian Medical University, Dongfang Hospital of Xiamen University, School of Medicine, Xiamen University, 900th Hospital of PLA Joint Logistic Support Force, Fuzhou, 350001, China. ⁶ Department of Pulmonary and Critical Care Medicine, The Affiliated Hospital of Putian University, Putian, 351100, China. ⁷ Department of Pulmonary and Critical Care Medicine, Fujian Medical University Union Hospital, Fuzhou, 350001, China. ⁸ Department of Pulmonary and Critical Care Medicine, Fuzhou Pulmonary Hospital of Fujian, Fujian Medical University Clinical Teaching Hospital, Fuzhou, 350001, China. ⁹ Department of Pulmonary and Critical Care Medicine, The Second Hospital of Nanping, Nanping, 353000, China. ¹⁰ Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China. liuzeyisuda@163.com. ¹¹ Department of Pulmonary and Critical Care Medicine, Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China. xbaosong@126.com. ¹² Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, 350003, China. laiguoxiang2007@163.com. ¹³ Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China. huang_jian_an@163.com.）

出处： Infectious diseases of poverty 2026

关键词： Antifungal therapy;Cryptococcal antigen;Cryptococcal meningitis;Cryptococcosis;Immune status;Prognosis.

摘要： Background: Cryptococcosis is a major opportunistic fungal infection with heterogeneous clinical outcomes; however, data on clinical features and prog ...

作者： Qiang Zhang¹;Yue Wang²;Xiao Ning Lin³;Yong Cheng Xu⁴;Miao Xu⁵;Xuan Lin⁶;Yue Lai⁷;Huan Liu⁸;Jian Lin Shen¹ （¹Central Laboratory, Affiliated Hospital of Putian University, Putian, China;²School of Basic Medicine Science, Key Laboratory of Translational Tumor Medicine in Fujian Province, Putian University, Putian, China;³Department of Orthopaedics, Affiliated Hospital of Putian University, Putian, China;⁴Department of Nephrology, Affiliated Hospital of Putian University, Putian, China;⁵School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China;⁶College of Biological Engineering, Putian University, Putian, China;⁷The First Clinical Medical School, Guangdong Medical University, Zhanjiang, China;⁸Department of Orthopaedics, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China）

出处： Artificial Cells, Nanomedicine, and Biotechnology 2026

关键词： Diabetic nephropathy;osteoporosis;low BMD;NLRP3;PBMCs;inflammasome

摘要： Diabetic nephropathy (DN), a major driver of end-stage kidney disease, elevates the risk for osteoporosis (OP) and its clinical precursor, low bone mi ...

作者： Zhimin Liu  ¹, Jiancheng Chen  ¹, Huifeng Wu  ², Xiaomei Li  ^{3   4}, Conghua Song  ^{5   6} （Affiliations ¹ Department of Emergency Medicine, The Affiliated Hospital of Putian University, Putian, 351100, China. ² Gastrointestinal Endoscopy Center, The Affiliated Hospital of Putian University, Putian, 351100, China. ³ School of Basic Medicine, Putian University, Putian, 351100, China. xmlee151@ptu.edu.cn. ⁴ Key Laboratory of Translational Tumor Medicine in Fujian Province, Putian University, Putian, 351100, China. xmlee151@ptu.edu.cn. ⁵ Gastrointestinal Endoscopy Center, The Affiliated Hospital of Putian University, Putian, 351100, China. kesongs@ptu.edu.cn. ⁶ Key Laboratory of Translational Tumor Medicine in Fujian Province, Putian University, Putian, 351100, China. kesongs@ptu.edu.cn.）

出处： European journal of medical research 2026

关键词： USP39;Immune infiltration;Pathway activation;Sepsis;Single-cell landscape.

摘要： Background: USP39 is involved in mRNA splicing and stress responses. This study analyzed USP39 expression and its clinical relevance in sepsis, aiming ...

作者： Zhiqiang Lin ¹, Douli Ke ¹, Mingyu Zheng ¹, Hanhan Qiu ¹, Binghuang Huang ¹, Yiting Wei ² （Affiliations ¹ Department of Electrocardiogram, Affiliated Hospital of PuTian University, Putian University, Putian, 351100, China. ² Department of Neurosurgery, The First Affiliated Hospital of Ningbo University, Ningbo, 315020, China. wytnbnc@163.com.）

出处： Naunyn-Schmiedeberg's archives of pharmacology 2026

关键词： Ferroptosis;GPX4;Ischemia/reperfusion;Morusin;Nrf2.

摘要： Myocardial ischemia/reperfusion injury (MIRI) involves exacerbated oxidative stress and ferroptosis, a regulated cell death driven by iron-dependent l ...

作者： Jianbin Ye ¹, Qingfeng Guo ², Yishen Hu ³, Ziyang Liu ⁴, Hu Zhu ⁵, Hongxin Hu ⁶, Xianwei Wu ⁷, Jia Xu ⁸ （Affiliations ¹ Putian University, School of Basic Medicine Science, Key Laboratory of Translational Tumor Medicine in Fujian Province, Putian, Fujian Province, 351100, China; College of Environmental and Biological Engineering, Putian, Fujian Province, 351100, China; China Fujian Medical University, School of Pharmacy, Fuzhou, Fujian Province, 350004, China. ² Putian University, School of Basic Medicine Science, Key Laboratory of Translational Tumor Medicine in Fujian Province, Putian, Fujian Province, 351100, China; China Fujian Medical University, School of Pharmacy, Fuzhou, Fujian Province, 350004, China. ³ Putian University, School of Basic Medicine Science, Key Laboratory of Translational Tumor Medicine in Fujian Province, Putian, Fujian Province, 351100, China; College of Environmental and Biological Engineering, Putian, Fujian Province, 351100, China. ⁴ Putian University, School of Basic Medicine Science, Key Laboratory of Translational Tumor Medicine in Fujian Province, Putian, Fujian Province, 351100, China. ⁵ Fujian-Taiwan Science and Technology Cooperation Base of Biomedical Materials and Tissue Engineering, Engineering Research Center of Industrial Biocatalysis, College of Chemistry and Materials Science, Fujian Normal University, Fuzhou, 350007, China. ⁶ The Affiliated Hospital of Putian University, Putian, Fujian Province, 351100, China. ⁷ The Affiliated Hospital of Putian University, Putian, Fujian Province, 351100, China. Electronic address: ptyygkwxw@ptu.edu.cn. ⁸ Putian University, School of Basic Medicine Science, Key Laboratory of Translational Tumor Medicine in Fujian Province, Putian, Fujian Province, 351100, China. Electronic address: xujia1986xujia@163.com.）

出处： International journal of biological macromolecules 2026

关键词： Bacterial cellulose;Package film;Seabuckthorn.

摘要： This study used seabuckthorn extract (SB) as substrate to enhance the production of bacterial cellulose (BC) membranes by Komagataeibacter rhaeticus ( ...