作者： Zhiyong Dong;Xiantu Qiu;Kujawa, Stacy A;Islam, S. M. Shariful;Jie Zhang （1 Department of Surgery, the Affiliated Hospital of Putian University, Putian 351100, China 2 Robert H. Lurie Medical Research Center, Feinberg School of Medicine, Northwestern University, Chicago 60611, USA 3 Institute of Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Faculty of Health, Deakin University, Melbourne 3280, Australia 4 Department of TCM, No. 988 Hospital of People''s Liberation Army, Zhengzhou 450042, China）

出处： Journal of Chinese Pharmaceutical Sciences 2019

关键词： Alternative therapies;Chinese herb medicine;Cinobufacini injection;Liver cancer;Meta-analysis;中草药;华蟾素注射液;替代疗法;肝癌;Meta-分析

摘要： Cinobufacini, a compound extracted from bufo toad, is a traditional Chinese medicine (TCM) that has been shown to have efficacy in cancer treatment. T ...

作者： Chen X.-H.;Shi Z.-G.;Lin H.-B.;Wu F.;Zheng F.;Wu C.-F.;Huang M.-W. （Department of Orthopedics, Affiliated Hospital of Putian University, Affiliated Hospital of Putian University Teaching Hospital of Fujian Medical University, Putian Hospital of Southern Medical University, Putian, China Department of Anesthesia, Beijing Chest Hospital, Capital Medical University, Beijing, China Department of Rehabilitation Medicine, Affiliated Hospital of Putian University, Affiliated Hospital of Putian University Teaching Hospital of Fujian Medical University, Affiliated Putian Hospital of Southern Medical University, Putian, China）

出处： European Review For Medical And Pharmacological Sciences 2019

关键词： Osteoporosis;Resveratrol;TNF-α

摘要： Objective: To investigate the protective effect of Resveratrol (RES) on TNF-α-induced inhibition of osteogenic differentiation, thus alleviating the p ...

作者： Wu MF;Xu KZ;Guo YG;Yu J;Wu Y;Lin LM （Department of Cardiology, Affiliated Hospital of Putian University, Putian, Fujian 351100, China）

出处： Cardiovascular Drugs And Therapy 2019

关键词： Apolipoprotein(a) antisense oligonucleotides;Atherosclerotic cardiovascular disease;Lipoprotein apheresis;Lipoprotein(a);PCSK9 inhibitors

摘要： Purpose: To review current knowledge of elevated lipoprotein(a) [Lp(a)] levels in relation to atherosclerotic cardiovascular disease (ASCVD) and discu ...

作者： Wu M;Xu K;Wu Y;Lin L （1.Department of Cardiology,Affiliated Hospital of Putian University,Putian,China）

出处： American Journal Of Cardiovascular Drugs: Drugs, Devices, And Other Interventions 2019

摘要： Heart failure (HF) with reduced ejection fraction (HFrEF) presents as the severest phenotype on the spectrum of HF. Although great progress has been m ...

作者： Xumei Pang¹;Peng Yin²;Jiliang Han³;Zhiqian Wang¹;Feng Zheng⁴;Xuanhuang Chen⁵ （1 Department of Oncology, Yidu Central Hospital of Weifang City, Weifang, China. 2 Department of Orthopedic Surgery, Yidu Central Hospital of Weifang City, Weifang, China. 3 Department of Radiotherapy, Yidu Central Hospital of Weifang City, Weifang, China. 4 Department of Orthopedics, The Affiliated Hospital of Putian University, Putian, Fujian, China. 5 Department of Orthopedics, The Affiliated Hospital of Putian University, Putian, Fujian, China. Electronic address: chenxuanhputian@163.com.）

出处： Pathology, research and practice 2019

关键词： Epithelial-mesenchymal transition;Invasion;Metastasis;Osteosarcoma;Prognosis;cPLA(2)a.

摘要： Background: Osteosarcoma (OS) patients with metastasis have very dismal prognoses, and lack effective target therapies. Overexpression of cytosolic ph ...

作者： 简陈兴，林力生，吴黎敏，李航，郑子芳，宋玉成，刘伟 （莆田学院附属医院微创外科；莆田学院附属医院乳腺外科）

出处： 中国修复重建外科杂志 2019

关键词： 乳腺癌；乳房再造；对称性；成形术

摘要： 目的 报告一种健侧乳房对称成形术,以解决乳腺癌术后即刻假体重建时双侧乳房不对称的问题。方法 2016年1月—2018年6月,收治11例女性乳腺癌患者。年龄34~64岁,平均49.6岁。左侧5例,右侧6例。病理诊断:浸润性癌3例,导管原位癌8例。肿瘤直径0.2~4.1 cm,平均2.5 cm。病程1~ ...

作者： 洪桂华，林华，庄宇珊，董娴 （莆田学院附属医院检验科）

出处： 中华医学遗传学杂志 2019

摘要： 患者 男,25岁.结婚1年多,妻未孕.夫妻表型及智力均正常,无不良嗜好,也未接触有毒有害物质,家系无近亲婚配及遗传病史.细胞遗传学检查:在征得知情同意后,抽取夫妇静脉血肝素抗凝,常规培养制片,G显带,计数30个中期分裂相,其妻核型未见异常,患者核型为46,XY,t(1;2)(p22;q21),inv ...

作者： 戴建立，李榕，刘海婷，简伟明，胡丽琴 （空军军医大学西京医院老年病科；云南省蒙自军分区保障处；福建省莆田学院附属医院儿科）

出处： 中华内科杂志 2019

关键词： 脑梗死；CTRP9；TOAST分型；分期

摘要： 本研究旨在探讨CTRP9在脑梗死发生发展过程中的变化及其意义.结果 表明,脑梗死组CTRP9水平低于对照组,尤其在大动脉粥样硬化亚组下降更明显;病程中CTRP9先下降后回升,在病程第4天至第10天降低明显,对脑梗死的诊断及分型、病程分期具有参考价值.Logistics回归分析提示高水平CTRP9为脑 ...

作者： 陈国立，吴献伟，胡洪新，林海滨 （莆田学院临床医学院；莆田学院附属医院）

出处： 中国骨质疏松杂志 2019

关键词： 降钙素基因相关肽；骨质疏松；脑缺血再灌注(I/R)；去势；海马；股骨头

摘要： 目的探讨降钙素基因相关肽(calcitonin gene-related peptide,CGRP)在去势大鼠合并脑缺血再灌注(I/R)中的损伤海马与骨质疏松股骨头中的跨种属组织关联性现象。方法建立去势大鼠模型后,采用线栓法建立短暂性右侧大脑中动脉闭塞海马损伤(I/R)模型,随机将大鼠分为正常组、假 ...

作者： Li, Hang;Lu, Shaohong;Chen, Yu;Zheng, Longzhi;Chen, Liangyuan;Ding, Haojie;Ding, Jianzu;Lou, Di;Liu, Fangfang;Zheng, Bin （1 Department of central laboratory, Affiliated Hospital of Putian University, Putian 351100, Fujian, PR China）

出处： Cellular Signalling 2019

关键词： AKT2;Colon cancer;HK2;Metastasis;Phosphorylation;Tumorigenesis

摘要： It has been well-established that AKT2 plays an important role in the development and progression of colon cancer; however, its precise function remai ...